Cytokeratin 18 anticorps (AA 391-483)

N° du produit ABIN965957

L’anticorps Souris Monoclonal anti-Cytokeratin 18 a été validé pour WB, IHC et ELISA. Il convient pour détecter Cytokeratin 18 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour Cytokeratin 18 anticorps (AA 391-483) (ABIN965957)

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 18 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4D11E4

Détail du produit anti-Cytokeratin 18 anticorps

Épitope: AA 391-483

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human Cytokeratin 18 (aa391-483) expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Cytokeratin 18 (ABIN965957)

Cheng, Liu, Ho, Chao, Pei, Hsu, Yeh, Ho, Tsai, Lai: "The influence of plectin deficiency on stability of cytokeratin18 in hepatocellular carcinoma." dans: Journal of molecular histology, Vol. 39, Issue 2, pp. 209-16, (2008) (PubMed).

Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." dans: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).

Détails sur Cytokeratin 18

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Autre désignation: Cytokeratin 18

Sujet: Cytokeratin 18, also known as CK18, CYK18, KRT18. Entrez Protein NP_000215. It encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Synonyms: CK18, CYK18, KRT18

Poids moléculaire: 48kDa

ID gène: 3875

Pathways: Apoptose, Caspase Cascade in Apoptosis